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Patronin governs minus-end-out orientation of dendritic microtubules to promote dendrite pruning in Drosophila

Class IV ddaC neurons specifically prune larval dendrites without affecting axons during Drosophila metamorphosis. ddaCs distribute the minus ends of microtubules (MTs) to dendrites but the plus ends to axons. However, a requirement of MT minus-end-binding proteins in dendrite-specific pruning remai...

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Detalles Bibliográficos
Autores principales: Wang, Yan, Rui, Menglong, Tang, Quan, Bu, Shufeng, Yu, Fengwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6438692/
https://www.ncbi.nlm.nih.gov/pubmed/30920370
http://dx.doi.org/10.7554/eLife.39964