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Extrasynaptic δ‐GABA(A) receptors are high‐affinity muscimol receptors

Muscimol, the major psychoactive ingredient in the mushroom Amanita muscaria, has been regarded as a universal non‐selective GABA‐site agonist. Deletion of the GABA(A) receptor (GABA(A)R) δ subunit in mice (δKO) leads to a drastic reduction in high‐affinity muscimol binding in brain sections and to...

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Detalles Bibliográficos
Autores principales: Benkherouf, Ali Y., Taina, Kaisa‐Riitta, Meera, Pratap, Aalto, Asko J., Li, Xiang‐Guo, Soini, Sanna L., Wallner, Martin, Uusi‐Oukari, Mikko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6438731/
https://www.ncbi.nlm.nih.gov/pubmed/30565258
http://dx.doi.org/10.1111/jnc.14646