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A Novel Synthetic Compound, Bismuth Zinc Citrate, Could Potentially Reduce Cisplatin-Induced Toxicity Without Compromising the Anticancer Effect Through Enhanced Expression of Antioxidant Protein

Cisplatin is a common anticancer drug, but it comes with significant nephrotoxicity. Further cisplatin-induced oxidative stress contributes to the pathogenesis of the nephrotoxicity. A new compound, BiZn, can potentially prevent this complication. We verified our postulation by in vitro and in vivo...

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Detalles Bibliográficos
Autores principales: Chan, Shing, Wang, Runming, Man, Kwan, Nicholls, John, Li, Hongyan, Sun, Hongzhe, Chan, Godfrey Chi-Fung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6438849/
https://www.ncbi.nlm.nih.gov/pubmed/30921749
http://dx.doi.org/10.1016/j.tranon.2019.02.003