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Perindopril and a Galectin-3 Inhibitor Improve Ischemic Heart Failure in Rabbits by Reducing Gal-3 Expression and Myocardial Fibrosis

Objective: Ventricular remodeling is considered the basis of heart failure and is involved in myocardial fibrosis. This study aimed to assess perindopril and a galectin-3 inhibitor (modified citrus pectin, MCP) for their effects on ventricular remodeling and myocardial fibrosis in rabbits with ische...

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Detalles Bibliográficos
Autores principales: Li, Sha, Li, Shuren, Hao, Xiao, Zhang, Yuehua, Deng, Wenhao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6438875/
https://www.ncbi.nlm.nih.gov/pubmed/30967790
http://dx.doi.org/10.3389/fphys.2019.00267