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Catching Latrophilin With Lasso: A Universal Mechanism for Axonal Attraction and Synapse Formation
Latrophilin-1 (LPHN1) was isolated as the main high-affinity receptor for α-latrotoxin from black widow spider venom, a powerful presynaptic secretagogue. As an adhesion G-protein-coupled receptor, LPHN1 is cleaved into two fragments, which can behave independently on the cell surface, but re-associ...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6438917/ https://www.ncbi.nlm.nih.gov/pubmed/30967757 http://dx.doi.org/10.3389/fnins.2019.00257 |