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Impact of the secretome of activated pancreatic stellate cells on growth and differentiation of pancreatic tumour cells
Pancreatic ductal adenocarcinoma (PDAC) exists in a complex desmoplastic microenvironment. As part of it, pancreatic stellate cells (PSCs) provide a fibrotic niche, stimulated by a dynamic communication between activated PSCs and tumour cells. Investigating how PSCs contribute to tumour development...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6438963/ https://www.ncbi.nlm.nih.gov/pubmed/30923340 http://dx.doi.org/10.1038/s41598-019-41740-x |