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Impact of the secretome of activated pancreatic stellate cells on growth and differentiation of pancreatic tumour cells

Pancreatic ductal adenocarcinoma (PDAC) exists in a complex desmoplastic microenvironment. As part of it, pancreatic stellate cells (PSCs) provide a fibrotic niche, stimulated by a dynamic communication between activated PSCs and tumour cells. Investigating how PSCs contribute to tumour development...

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Detalles Bibliográficos
Autores principales:	Marzoq, Aseel J., Mustafa, Shakhawan A., Heidrich, Luzia, Hoheisel, Jörg D., Alhamdani, Mohamed Saiel Saeed
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6438963/ https://www.ncbi.nlm.nih.gov/pubmed/30923340 http://dx.doi.org/10.1038/s41598-019-41740-x

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