Purinergic implication in amyotrophic lateral sclerosis—from pathological mechanisms to therapeutic perspectives

Amyotrophic lateral sclerosis (ALS) is a clinically heterogeneous disorder characterized by degeneration of upper motor neurons in the brainstem and lower motor neurons in the spinal cord. Multiple mechanisms of motor neuron injury have been implicated, including more than 20 different genetic facto...

Descripción completa

Detalles Bibliográficos
Autores principales: Cieślak, M., Roszek, K., Wujak, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2018
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6439052/
https://www.ncbi.nlm.nih.gov/pubmed/30430356
http://dx.doi.org/10.1007/s11302-018-9633-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6439052/
https://www.ncbi.nlm.nih.gov/pubmed/30430356
http://dx.doi.org/10.1007/s11302-018-9633-4

Ejemplares similares