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Purinergic implication in amyotrophic lateral sclerosis—from pathological mechanisms to therapeutic perspectives
Amyotrophic lateral sclerosis (ALS) is a clinically heterogeneous disorder characterized by degeneration of upper motor neurons in the brainstem and lower motor neurons in the spinal cord. Multiple mechanisms of motor neuron injury have been implicated, including more than 20 different genetic facto...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer Netherlands
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6439052/ https://www.ncbi.nlm.nih.gov/pubmed/30430356 http://dx.doi.org/10.1007/s11302-018-9633-4 |