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Solution NMR assignment of the ARC4 domain of human tankyrase 2

Tankyrases are poly(ADP-ribose)polymerases (PARPs) which recognize their substrates via their ankyrin repeat cluster (ARC) domains. The human tankyrases (TNKS/TNKS2) contain five ARCs in their extensive N-terminal region; of these, four bind peptides present within tankyrase interactors and substrat...

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Detalles Bibliográficos
Autores principales: Zaleska, Mariola, Pollock, Katie, Collins, Ian, Guettler, Sebastian, Pfuhl, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6439159/
https://www.ncbi.nlm.nih.gov/pubmed/30847846
http://dx.doi.org/10.1007/s12104-019-09887-w