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Locus coeruleus MRI contrast is reduced in Alzheimer's disease dementia and correlates with CSF Aβ levels

INTRODUCTION: This study aimed to assess how interindividual differences in locus coeruleus (LC) magnetic resonance imaging (MRI) contrast relate to cerebrospinal fluid (CSF) biomarkers of Alzheimer's disease (AD). METHODS: LC MRI contrast was quantified in 73 individuals from the DZNE Longitud...

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Detalles Bibliográficos
Autores principales: Betts, Matthew J., Cardenas-Blanco, Arturo, Kanowski, Martin, Spottke, Annika, Teipel, Stefan J., Kilimann, Ingo, Jessen, Frank, Düzel, Emrah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6439222/
https://www.ncbi.nlm.nih.gov/pubmed/30976648
http://dx.doi.org/10.1016/j.dadm.2019.02.001