ABCB1 and BMI1 mRNA expression in patients with chronic myeloid leukemia: impact on imatinib efficacy

BACKGROUND: ATP-binding cassette transporters are important in the mechanism of multidrug resistance. ABCB1 displays a high affinity for imatinib. BMI1 is a polycomb group protein thought to be overexpressed in leukemic cells. METHODS: This study was conducted to investigate the prognostic value of...

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Detalles Bibliográficos
Autores principales: Bedewy, Ahmed M. L., Elmaghraby, Shereen M., Kandil, Noha S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society of Hematology; Korean Society of Blood and Marrow Transplantation; Korean Society of Pediatric Hematology-Oncology; Korean Society on Thrombosis and Hemostasis 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6439291/
https://www.ncbi.nlm.nih.gov/pubmed/30956965
http://dx.doi.org/10.5045/br.2019.54.1.57

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6439291/
https://www.ncbi.nlm.nih.gov/pubmed/30956965
http://dx.doi.org/10.5045/br.2019.54.1.57

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