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Repeated Sigma-1 Receptor Antagonist MR309 Administration Modulates Central Neuropathic Pain Development After Spinal Cord Injury in Mice

Up to two-thirds of patients affected by spinal cord injury (SCI) develop central neuropathic pain (CNP), which has a high impact on their quality of life. Most of the patients are largely refractory to current treatments, and new pharmacological strategies are needed. Recently, it has been shown th...

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Detalles Bibliográficos
Autores principales: Castany, Sílvia, Codony, Xavier, Zamanillo, Daniel, Merlos, Manuel, Verdú, Enrique, Boadas-Vaello, Pere
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6439356/
https://www.ncbi.nlm.nih.gov/pubmed/30967775
http://dx.doi.org/10.3389/fphar.2019.00222