Plinabulin, an inhibitor of tubulin polymerization, targets KRAS signaling through disruption of endosomal recycling

Constitutive activation of Kirsten rat sarcoma viral oncogene homolog (KRAS) is the most common oncogenic event in certain types of human cancer and is associated with poor patient survival. Small molecule signaling inhibitors have improved the clinical outcomes of patients with various cancer types...

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Detalles Bibliográficos
Autores principales: Cimino, Patrick J., Huang, Lan, Du, Lihua, Wu, Yanping, Bishop, Jamie, Dalsing-Hernandez, Jessica, Kotlarczyk, Kari, Gonzales, Paul, Carew, Jennifer, Nawrocki, Steffan, Jordan, Mary Ann, Wilson, Leslie, Lloyd, G. Kenneth, Wirsching, Hans-Georg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6439430/
https://www.ncbi.nlm.nih.gov/pubmed/30972217
http://dx.doi.org/10.3892/br.2019.1196

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6439430/
https://www.ncbi.nlm.nih.gov/pubmed/30972217
http://dx.doi.org/10.3892/br.2019.1196

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