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Association of Mutations Contributing to Clonal Hematopoiesis With Prognosis in Chronic Ischemic Heart Failure

IMPORTANCE: Somatic mutations causing clonal expansion of hematopoietic cells (clonal hematopoiesis of indeterminate potential [CHIP]) are increased with age and associated with atherosclerosis and inflammation. Age and inflammation are the major risk factors for heart failure, yet the association o...

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Detalles Bibliográficos
Autores principales: Dorsheimer, Lena, Assmus, Birgit, Rasper, Tina, Ortmann, Christina A., Ecke, Andreas, Abou-El-Ardat, Khalil, Schmid, Tobias, Brüne, Bernhard, Wagner, Sebastian, Serve, Hubert, Hoffmann, Jedrzej, Seeger, Florian, Dimmeler, Stefanie, Zeiher, Andreas M., Rieger, Michael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Medical Association 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6439691/
https://www.ncbi.nlm.nih.gov/pubmed/30566180
http://dx.doi.org/10.1001/jamacardio.2018.3965