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New insights emerge as antibody repertoire diversification meets chromosome conformation
Vast repertoires of unique antigen receptors are created in developing lymphocytes. The antigen receptor loci contain many variable (V), diversity (D), and joining (J) gene segments that are arrayed across very large genomic expanses and are joined to form variable-region exons. This process creates...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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F1000 Research Limited
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6439775/ https://www.ncbi.nlm.nih.gov/pubmed/30984378 http://dx.doi.org/10.12688/f1000research.17358.1 |