Constructing effective energy functions for protein structure prediction through broadening attraction-basin and reverse Monte Carlo sampling

BACKGROUND: The ab initio approaches to protein structure prediction usually employ the Monte Carlo technique to search the structural conformation that has the lowest energy. However, the widely-used energy functions are usually ineffective for conformation search. How to construct an effective ene...

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Detalles Bibliográficos
Autores principales: Wang, Chao, Wei, Yi, Zhang, Haicang, Kong, Lupeng, Sun, Shiwei, Zheng, Wei-Mou, Bu, Dongbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6439974/
https://www.ncbi.nlm.nih.gov/pubmed/30925867
http://dx.doi.org/10.1186/s12859-019-2652-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6439974/
https://www.ncbi.nlm.nih.gov/pubmed/30925867
http://dx.doi.org/10.1186/s12859-019-2652-5

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