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Differentiation of adult human retinal pigment epithelial cells into dopaminergic-like cells in vitro and in the recipient monkey brain

BACKGROUND: Cell therapy is proposed to be a potential treatment for Parkinson’s disease (PD). Although fetal retinal pigment epithelial (RPE) cells have been tested in trials for treating PD patients, controversy has been raised over the issue of whether such cells can be reprogrammed into dopamine...

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Detalles Bibliográficos
Autores principales: Li, Sha, Zhang, Han, Wang, Aifang, Liu, Yan, Liu, Houqi, Yue, Feng, Abulaiti, Xianmixinuer, Zhang, Caiqiao, Li, Lingsong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6440004/
https://www.ncbi.nlm.nih.gov/pubmed/30922214
http://dx.doi.org/10.1186/s10020-019-0076-3