Cargando…

PRMT5 enhances tumorigenicity and glycolysis in pancreatic cancer via the FBW7/cMyc axis

BACKGROUND: The epigenetic factor protein arginine methyltransferase 5 (PRMT5) has been reported to play vital roles in a wide range of cellular processes, such as gene transcription, genomic organization, differentiation and cell cycle control. However, its role in pancreatic cancer remains unclear...

Descripción completa

Detalles Bibliográficos
Autores principales: Qin, Yi, Hu, Qiangsheng, Xu, Jin, Ji, Shunrong, Dai, Weixing, Liu, Wensheng, Xu, Wenyan, Sun, Qiqing, Zhang, Zheng, Ni, Quanxing, Zhang, Bo, Yu, Xianjun, Xu, Xiaowu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6440122/
https://www.ncbi.nlm.nih.gov/pubmed/30922330
http://dx.doi.org/10.1186/s12964-019-0344-4