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Development of a novel selection/counter-selection system for chromosomal gene integrations and deletions in lactic acid bacteria
BACKGROUND: The underlying mechanisms by which probiotic lactic acid bacteria (LAB) enhance the health of the consumer have not been fully elucidated. Verification of probiotic modes of action can be achieved by using single- or multiple-gene knockout analyses of bacterial mutants in in vitro or in...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6440147/ https://www.ncbi.nlm.nih.gov/pubmed/30922229 http://dx.doi.org/10.1186/s12867-019-0127-x |