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Development of a novel selection/counter-selection system for chromosomal gene integrations and deletions in lactic acid bacteria

BACKGROUND: The underlying mechanisms by which probiotic lactic acid bacteria (LAB) enhance the health of the consumer have not been fully elucidated. Verification of probiotic modes of action can be achieved by using single- or multiple-gene knockout analyses of bacterial mutants in in vitro or in...

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Detalles Bibliográficos
Autores principales: Van Zyl, Winschau F., Dicks, Leon M. T., Deane, Shelly M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6440147/
https://www.ncbi.nlm.nih.gov/pubmed/30922229
http://dx.doi.org/10.1186/s12867-019-0127-x

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