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Early Stage Alterations in White Matter and Decreased Functional Interhemispheric Hippocampal Connectivity in the 3xTg Mouse Model of Alzheimer’s Disease

Alzheimer’s disease (AD) is characterized in the late stages by amyloid-β (Aβ) plaques and neurofibrillary tangles. Nevertheless, recent evidence has indicated that early changes in cerebral connectivity could compromise cognitive functions even before the appearance of the classical neuropathologic...

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Detalles Bibliográficos
Autores principales: Manno, Francis A. M., Isla, Arturo G., Manno, Sinai H. C., Ahmed, Irfan, Cheng, Shuk Han, Barrios, Fernando A., Lau, Condon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6440287/
https://www.ncbi.nlm.nih.gov/pubmed/30967770
http://dx.doi.org/10.3389/fnagi.2019.00039