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Early Stage Alterations in White Matter and Decreased Functional Interhemispheric Hippocampal Connectivity in the 3xTg Mouse Model of Alzheimer’s Disease
Alzheimer’s disease (AD) is characterized in the late stages by amyloid-β (Aβ) plaques and neurofibrillary tangles. Nevertheless, recent evidence has indicated that early changes in cerebral connectivity could compromise cognitive functions even before the appearance of the classical neuropathologic...
Autores principales: | Manno, Francis A. M., Isla, Arturo G., Manno, Sinai H. C., Ahmed, Irfan, Cheng, Shuk Han, Barrios, Fernando A., Lau, Condon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6440287/ https://www.ncbi.nlm.nih.gov/pubmed/30967770 http://dx.doi.org/10.3389/fnagi.2019.00039 |
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