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Structural Diversity of Ultralong CDRH3s in Seven Bovine Antibody Heavy Chains

Antigen recognition by mammalian antibodies represents the most diverse setting for protein-protein interactions, because antibody variable regions contain exceptionally diverse variable gene repertoires of DNA sequences containing combinatorial, non-templated junctional mutational diversity. Some a...

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Detalles Bibliográficos
Autores principales: Dong, Jinhui, Finn, Jessica A., Larsen, Peter A., Smith, Timothy P. L., Crowe, James E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6440498/
https://www.ncbi.nlm.nih.gov/pubmed/30967877
http://dx.doi.org/10.3389/fimmu.2019.00558