Novel Implementation of Genotype‐Guided Proton Pump Inhibitor Medication Therapy in Children: A Pilot, Randomized, Multisite Pragmatic Trial

The efficacy of proton pump inhibitor (PPI) medications is highly dependent on plasma concentrations, which varies considerably due to cytochrome P450 (CYP2C19) genetic variation. We conducted a pragmatic, pilot study of CYP2C19 genotype‐guided pediatric dosing of PPI medications. Children aged 5–17...

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Detalles Bibliográficos
Autores principales: Cicali, Emily J., Blake, Kathryn, Gong, Yan, Mougey, Edward B., Al‐Atrash, Hadeel, Chambers, Nancy, Denham, Jolanda, Evans, Jonathan, George, Donald E., Gomez, Roberto, Palomo, Pablo, Taufiq, Salik, Johnson, Julie A., Lima, John J., Franciosi, James P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6440564/
https://www.ncbi.nlm.nih.gov/pubmed/30341969
http://dx.doi.org/10.1111/cts.12589

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6440564/
https://www.ncbi.nlm.nih.gov/pubmed/30341969
http://dx.doi.org/10.1111/cts.12589

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