Ceftazidime‐Avibactam Population Pharmacokinetic Modeling and Pharmacodynamic Target Attainment Across Adult Indications and Patient Subgroups

Ceftazidime‐avibactam is a novel β‐lactam/β‐lactamase inhibitor combination for the treatment of serious infections caused by resistant gram‐negative pathogens. Population pharmacokinetic (PopPK) models were built to incorporate pharmacokinetic (PK) data from five phase III trials in patients with c...

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Detalles Bibliográficos
Autores principales: Li, Jianguo, Lovern, Mark, Green, Michelle L., Chiu, Joannellyn, Zhou, Diansong, Comisar, Craig, Xiong, Yuan, Hing, Jeremy, MacPherson, Merran, Wright, James G., Riccobene, Todd, Carrothers, Timothy J., Das, Shampa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6440567/
https://www.ncbi.nlm.nih.gov/pubmed/30221827
http://dx.doi.org/10.1111/cts.12585

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6440567/
https://www.ncbi.nlm.nih.gov/pubmed/30221827
http://dx.doi.org/10.1111/cts.12585

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