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Pharmacokinetic and Pharmacodynamic Considerations in the Design of Therapeutic Antibodies
The design and development of therapeutic monoclonal antibodies (mAbs) through optimizing their pharmacokinetic (PK) and pharmacodynamic (PD) properties is crucial to improve efficacy while minimizing adverse events. Many of these properties are interdependent, which highlights the inherent challeng...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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John Wiley and Sons Inc.
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6440574/ https://www.ncbi.nlm.nih.gov/pubmed/30414357 http://dx.doi.org/10.1111/cts.12597 |