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Loss of miR-451a enhances SPARC production during myogenesis

MicroRNAs (miRNAs) are small noncoding RNAs that critically regulate gene expression. Their abundance and function have been linked to a range of physiologic and pathologic processes. In aged monkey muscle, miR-451a and miR-144-3p were far more abundant than in young monkey muscle. This observation...

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Detalles Bibliográficos
Autores principales: Munk, Rachel, Martindale, Jennifer L., Yang, Xiaoling, Yang, Jen-Hao, Grammatikakis, Ioannis, Di Germanio, Clara, Mitchell, Sarah J., de Cabo, Rafael, Lehrmann, Elin, Zhang, Yongqing, Becker, Kevin G., Raz, Vered, Gorospe, Myriam, Abdelmohsen, Kotb, Panda, Amaresh C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6440632/
https://www.ncbi.nlm.nih.gov/pubmed/30925184
http://dx.doi.org/10.1371/journal.pone.0214301