Phosphorylation of a serine/proline-rich motif in oxysterol binding protein-related protein 4L (ORP4L) regulates cholesterol and vimentin binding

The family of oxysterol binding protein (OSBP) and OSBP-related proteins (ORPs) mediate sterol and phospholipid transfer and signaling at membrane contact sites (MCS). The activity of OSBP at MCS is regulated by phosphorylation, but whether this applies to ORPs is unknown. Here we report the functio...

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Detalles Bibliográficos
Autores principales: Pietrangelo, Antonietta, Ridgway, Neale D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6440634/
https://www.ncbi.nlm.nih.gov/pubmed/30925160
http://dx.doi.org/10.1371/journal.pone.0214768

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6440634/
https://www.ncbi.nlm.nih.gov/pubmed/30925160
http://dx.doi.org/10.1371/journal.pone.0214768

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