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Optimal parameter identification of synthetic gene networks using harmony search algorithm
Computational modeling of engineered gene circuits is an important while challenged task in systems biology. In order to describe and predict the response behaviors of genetic circuits using reliable model parameters, this paper applies an optimal experimental design(OED) method to obtain input sign...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6440652/ https://www.ncbi.nlm.nih.gov/pubmed/30925150 http://dx.doi.org/10.1371/journal.pone.0213977 |