Exosomal delivery of doxorubicin enables rapid cell entry and enhanced in vitro potency

Doxorubicin is a chemotherapeutic agent that is commonly used to treat a broad range of cancers. However, significant cardiotoxicity, associated with prolonged exposure to doxorubicin, limits its continued therapeutic use. One strategy to prevent the uptake of doxorubicin into cardiac cells is the e...

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Detalles Bibliográficos
Autores principales: Schindler, Christina, Collinson, Andie, Matthews, Carl, Pointon, Amy, Jenkinson, Lesley, Minter, Ralph R., Vaughan, Tristan J., Tigue, Natalie J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6440694/
https://www.ncbi.nlm.nih.gov/pubmed/30925190
http://dx.doi.org/10.1371/journal.pone.0214545

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6440694/
https://www.ncbi.nlm.nih.gov/pubmed/30925190
http://dx.doi.org/10.1371/journal.pone.0214545

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