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Exosomal delivery of doxorubicin enables rapid cell entry and enhanced in vitro potency
Doxorubicin is a chemotherapeutic agent that is commonly used to treat a broad range of cancers. However, significant cardiotoxicity, associated with prolonged exposure to doxorubicin, limits its continued therapeutic use. One strategy to prevent the uptake of doxorubicin into cardiac cells is the e...
Autores principales: | Schindler, Christina, Collinson, Andie, Matthews, Carl, Pointon, Amy, Jenkinson, Lesley, Minter, Ralph R., Vaughan, Tristan J., Tigue, Natalie J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6440694/ https://www.ncbi.nlm.nih.gov/pubmed/30925190 http://dx.doi.org/10.1371/journal.pone.0214545 |
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