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ANDROGEN SIGNALING IS ESSENTIAL FOR DEVELOPMENT OF PROSTATE CANCER INITIATED FROM PROSATIC BASAL CELLS

Emerging evidence has shown that both prostatic basal and luminal cells are able to initiate oncogenic transformation. However, despite the diversity of tumor initiating cells, most prostate cancer cells express the androgen receptor (AR) and depend on androgens for their growth and expansion, impli...

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Detalles Bibliográficos
Autores principales: He, Yongfeng, Hooker, Erika, Yu, Eun-Jeong, Cunha, Gerald R., Liao, Lan, Xu, Jianming, Earl, Andrew, Wu, Huiqing, Gonzalgo, Michael L., Sun, Zijie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6440846/
https://www.ncbi.nlm.nih.gov/pubmed/30510232
http://dx.doi.org/10.1038/s41388-018-0583-7