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Quantitative relationships between SMAD dynamics and target gene activation kinetics in single live cells
The transduction of extracellular signals through signaling pathways that culminate in a transcriptional response is central to many biological processes. However, quantitative relationships between activities of signaling pathway components and transcriptional output of target genes remain poorly e...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6440972/ https://www.ncbi.nlm.nih.gov/pubmed/30926874 http://dx.doi.org/10.1038/s41598-019-41870-2 |