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USP32 regulates late endosomal transport and recycling through deubiquitylation of Rab7

The endosomal system is a highly dynamic multifunctional organelle, whose complexity is regulated in part by reversible ubiquitylation. Despite the wide-ranging influence of ubiquitin in endosomal processes, relatively few enzymes utilizing ubiquitin have been described to control endosome integrity...

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Detalles Bibliográficos
Autores principales: Sapmaz, Aysegul, Berlin, Ilana, Bos, Erik, Wijdeven, Ruud H., Janssen, Hans, Konietzny, Rebecca, Akkermans, Jimmy J., Erson-Bensan, Ayse E., Koning, Roman I., Kessler, Benedikt M., Neefjes, Jacques, Ovaa, Huib
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6440979/
https://www.ncbi.nlm.nih.gov/pubmed/30926795
http://dx.doi.org/10.1038/s41467-019-09437-x