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Multifunctional Gold Nanoparticles Overcome MicroRNA Regulatory Network Mediated-Multidrug Resistant Leukemia

Resistance to chemotherapy and molecularly targeted therapies is a major problem in current leukemia treatments. Here, we investigated cross-talk between the miR-221 network and P-glycoprotein (P-gp) in doxorubicin-induced drug resistance of leukemia cells. Multifunctional gold nanoparticles were de...

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Detalles Bibliográficos
Autores principales: Deng, Rong, Ji, Bai, Yu, Hongliang, Bao, Wei, Yang, Zhuoqi, Yu, Ying, Cui, Yahan, Du, Yangyang, Song, Meiyu, Liu, Shujun, Meguellati, Kamel, Yan, Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6440980/
https://www.ncbi.nlm.nih.gov/pubmed/30926883
http://dx.doi.org/10.1038/s41598-019-41866-y