Protein kinase CK2-dependent aerobic glycolysis-induced lactate dehydrogenase A enhances the migration and invasion of cancer cells

We investigated the intracellular metabolic fluxes of protein kinase CK2-activating (Cα OE) cells and role of lactate dehydrogenase A (LDHA) as a contributor of tumorigenesis after reprogrammed glucose metabolism. Facilitated aerobic glycolysis was confirmed via isotope tracer analysis, in which (13...

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Detalles Bibliográficos
Autores principales: Im, Dae-Kyun, Cheong, Heesun, Lee, Jong Suk, Oh, Min-Kyu, Yang, Kyung Mi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441004/
https://www.ncbi.nlm.nih.gov/pubmed/30926903
http://dx.doi.org/10.1038/s41598-019-41852-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441004/
https://www.ncbi.nlm.nih.gov/pubmed/30926903
http://dx.doi.org/10.1038/s41598-019-41852-4

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