Computer aided protein engineering to enhance the thermo-stability of CXCR1- T4 lysozyme complex

CXCR1, a member in G-protein coupled receptor (GPCR) family, binds to chemokine interleukin-8 (IL-8) specifically and transduces signals to mediate immune and inflammatory responses. Despite the importance of CXCR1, high-resolution structure determination is hindered by the challenges in crystalliza...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Yang, Park, Jae-Hyun, Lupala, Cecylia Severin, Yun, Ji-Hye, Jin, Zeyu, Huang, Lanqing, Li, Xuanxuan, Tang, Leihan, Lee, Weontae, Liu, Haiguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441008/
https://www.ncbi.nlm.nih.gov/pubmed/30926935
http://dx.doi.org/10.1038/s41598-019-41838-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441008/
https://www.ncbi.nlm.nih.gov/pubmed/30926935
http://dx.doi.org/10.1038/s41598-019-41838-2

Ejemplares similares