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Structure mapping of dengue and Zika viruses reveals functional long-range interactions

Dengue (DENV) and Zika (ZIKV) viruses are clinically important members of the Flaviviridae family with an 11 kb positive strand RNA genome that folds to enable virus function. Here, we perform structure and interaction mapping on four DENV and ZIKV strains inside virions and in infected cells. Compa...

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Detalles Bibliográficos
Autores principales: Huber, Roland G., Lim, Xin Ni, Ng, Wy Ching, Sim, Adelene Y. L., Poh, Hui Xian, Shen, Yang, Lim, Su Ying, Sundstrom, Karin B., Sun, Xuyang, Aw, Jong Ghut, Too, Horng Khit, Boey, Peng Hee, Wilm, Andreas, Chawla, Tanu, Choy, Milly M., Jiang, Lu, de Sessions, Paola Florez, Loh, Xian Jun, Alonso, Sylvie, Hibberd, Martin, Nagarajan, Niranjan, Ooi, Eng Eong, Bond, Peter J., Sessions, October M., Wan, Yue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441010/
https://www.ncbi.nlm.nih.gov/pubmed/30926818
http://dx.doi.org/10.1038/s41467-019-09391-8