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Phosphatidylethanolamine made in the inner mitochondrial membrane is essential for yeast cytochrome bc(1) complex function

Of the four separate PE biosynthetic pathways in eukaryotes, one occurs in the mitochondrial inner membrane (IM) and is executed by phosphatidylserine decarboxylase (Psd1). Deletion of Psd1 is lethal in mice and compromises mitochondrial function. We hypothesize that this reflects inefficient import...

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Detalles Bibliográficos
Autores principales: Calzada, Elizabeth, Avery, Erica, Sam, Pingdewinde N., Modak, Arnab, Wang, Chunyan, McCaffery, J. Michael, Han, Xianlin, Alder, Nathan N., Claypool, Steven M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441012/
https://www.ncbi.nlm.nih.gov/pubmed/30926815
http://dx.doi.org/10.1038/s41467-019-09425-1