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Phosphatidylethanolamine made in the inner mitochondrial membrane is essential for yeast cytochrome bc(1) complex function
Of the four separate PE biosynthetic pathways in eukaryotes, one occurs in the mitochondrial inner membrane (IM) and is executed by phosphatidylserine decarboxylase (Psd1). Deletion of Psd1 is lethal in mice and compromises mitochondrial function. We hypothesize that this reflects inefficient import...
Autores principales: | Calzada, Elizabeth, Avery, Erica, Sam, Pingdewinde N., Modak, Arnab, Wang, Chunyan, McCaffery, J. Michael, Han, Xianlin, Alder, Nathan N., Claypool, Steven M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441012/ https://www.ncbi.nlm.nih.gov/pubmed/30926815 http://dx.doi.org/10.1038/s41467-019-09425-1 |
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