Proximal and distal control for ligand binding in neuroglobin: role of the CD loop and evidence for His64 gating

Neuroglobin (Ngb) is predominantly expressed in neurons of the central and peripheral nervous systems and it clearly seems to be involved in neuroprotection. Engineering Ngb to observe structural and dynamic alterations associated with perturbation in ligand binding might reveal important structural...

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Detalles Bibliográficos
Autores principales: Exertier, Cécile, Milazzo, Lisa, Freda, Ida, Montemiglio, Linda Celeste, Scaglione, Antonella, Cerutti, Gabriele, Parisi, Giacomo, Anselmi, Massimiliano, Smulevich, Giulietta, Savino, Carmelinda, Vallone, Beatrice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441039/
https://www.ncbi.nlm.nih.gov/pubmed/30926858
http://dx.doi.org/10.1038/s41598-019-41780-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441039/
https://www.ncbi.nlm.nih.gov/pubmed/30926858
http://dx.doi.org/10.1038/s41598-019-41780-3

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