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Interleukin-8/CXCR2 signaling regulates therapy-induced plasticity and enhances tumorigenicity in glioblastoma

Emerging evidence reveals enrichment of glioma-initiating cells (GICs) following therapeutic intervention. One factor known to contribute to this enrichment is cellular plasticity—the ability of glioma cells to attain multiple phenotypes. To elucidate the molecular mechanisms governing therapy-induc...

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Detalles Bibliográficos
Autores principales: Hasan, Tanwir, Caragher, Seamus P., Shireman, Jack M., Park, Cheol H., Atashi, Fatemeh, Baisiwala, Shivani, Lee, Gina, Guo, Donna, Wang, Jennifer Y., Dey, Mahua, Wu, Meijing, Lesniak, Maciej S., Horbinski, Craig M., James, C. David, Ahmed, Atique U.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441047/
https://www.ncbi.nlm.nih.gov/pubmed/30926789
http://dx.doi.org/10.1038/s41419-019-1387-6