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Interleukin-8/CXCR2 signaling regulates therapy-induced plasticity and enhances tumorigenicity in glioblastoma
Emerging evidence reveals enrichment of glioma-initiating cells (GICs) following therapeutic intervention. One factor known to contribute to this enrichment is cellular plasticity—the ability of glioma cells to attain multiple phenotypes. To elucidate the molecular mechanisms governing therapy-induc...
Autores principales: | Hasan, Tanwir, Caragher, Seamus P., Shireman, Jack M., Park, Cheol H., Atashi, Fatemeh, Baisiwala, Shivani, Lee, Gina, Guo, Donna, Wang, Jennifer Y., Dey, Mahua, Wu, Meijing, Lesniak, Maciej S., Horbinski, Craig M., James, C. David, Ahmed, Atique U. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441047/ https://www.ncbi.nlm.nih.gov/pubmed/30926789 http://dx.doi.org/10.1038/s41419-019-1387-6 |
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