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The formin Drosophila homologue of Diaphanous2 (Diaph2) controls microtubule dynamics in colorectal cancer cells independent of its FH2-domain

In this study, we analyzed the functional role of the formin Drosophila Homologue of Diaphanous2 (Diaph2) in colorectal cancer cells. We show that stable down-regulation of Diaph2 expression in HT29 cells decreased chromosome alignment and the velocity of chromosome movement during M-phase, thus red...

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Detalles Bibliográficos
Autores principales: Grueb, Saskia S., Muhs, Stefanie, Popp, Yannes, Schmitt, Sebastian, Geyer, Matthias, Lin, Yuan-Na, Windhorst, Sabine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441084/
https://www.ncbi.nlm.nih.gov/pubmed/30926831
http://dx.doi.org/10.1038/s41598-019-41731-y