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HDAC1 and HDAC2 independently regulate common and specific intrinsic responses in murine enteroids

Both HDAC1 and HDAC2 are class I deacetylases acting as erasers of lysine-acetyl marks on histones and non-histone proteins. Several histone deacetylase inhibitors, either endogenous to the cell, such as the ketogenic β-hydroxybutyrate metabolite, or exogenous, such as butyrate, a microbial-derived...

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Detalles Bibliográficos
Autores principales: Gonneaud, Alexis, Turgeon, Naomie, Jones, Christine, Couture, Cassandra, Lévesque, Dominique, Boisvert, François-Michel, Boudreau, François, Asselin, Claude
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441098/
https://www.ncbi.nlm.nih.gov/pubmed/30926862
http://dx.doi.org/10.1038/s41598-019-41842-6