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Ligand design strategies to increase stability of gadolinium-based magnetic resonance imaging contrast agents

Gadolinium(III) complexes have been widely utilised as magnetic resonance imaging (MRI) contrast agents for decades. In recent years however, concerns have developed about their toxicity, believed to derive from demetallation of the complexes in vivo, and the relatively large quantities of compound...

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Detalles Bibliográficos
Autores principales: Clough, Thomas J., Jiang, Lijun, Wong, Ka-Leung, Long, Nicholas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441101/
https://www.ncbi.nlm.nih.gov/pubmed/30926784
http://dx.doi.org/10.1038/s41467-019-09342-3