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Hyperactivation of proprioceptors induces microglia-mediated long-lasting pain in a rat model of chronic fatigue syndrome

BACKGROUND: Patients diagnosed with chronic fatigue syndrome (CFS) or fibromyalgia experience chronic pain. Concomitantly, the rat model of CFS exhibits microglial activation in the lumbar spinal cord and pain behavior without peripheral tissue damage and/or inflammation. The present study addressed...

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Detalles Bibliográficos
Autores principales: Yasui, Masaya, Menjyo, Yuki, Tokizane, Kyohei, Shiozawa, Akiko, Tsuda, Makoto, Inoue, Kazuhide, Kiyama, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441145/
https://www.ncbi.nlm.nih.gov/pubmed/30927920
http://dx.doi.org/10.1186/s12974-019-1456-x