PGK1 facilities cisplatin chemoresistance by triggering HSP90/ERK pathway mediated DNA repair and methylation in endometrial endometrioid adenocarcinoma

BACKGROUND: Endometrial carcinoma represents one of the most common cancer types of the female reproductive tract. If diagnosed at an early stage, the 5-year survival rate is promising. However, recurrence and chemoresistance remain problematic for at least 15% of the patients. In the present study,...

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Detalles Bibliográficos
Autores principales: Zhou, Jing-Wei, Tang, Juan-Juan, Sun, Wei, Wang, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441178/
https://www.ncbi.nlm.nih.gov/pubmed/30925862
http://dx.doi.org/10.1186/s10020-019-0079-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441178/
https://www.ncbi.nlm.nih.gov/pubmed/30925862
http://dx.doi.org/10.1186/s10020-019-0079-0

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