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mRNA-to-protein translation in hypoxia

Cells respond to hypoxia by shifting cellular processes from general housekeeping functions to activating specialized hypoxia-response pathways. Oxygen plays an important role in generating ATP to maintain a productive rate of protein synthesis in normoxia. In hypoxia, the rate of the canonical prot...

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Detalles Bibliográficos
Autores principales: Chee, Nancy T., Lohse, Ines, Brothers, Shaun P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441220/
https://www.ncbi.nlm.nih.gov/pubmed/30925920
http://dx.doi.org/10.1186/s12943-019-0968-4